SEPTIN7 and S100A4

Data Source:
HPRD (in vitro)

		SEPTIN7	S100A4
Description		septin 7	S100 calcium binding protein A4
Image
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Spindle Cytosol Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Cell Division Site Cleavage Furrow Extracellular Exosome Sperm Annulus Non-motile Cilium	Extracellular Region Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity	RNA Binding Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Spermatogenesis Regulation Of Embryonic Cell Shape Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		MAPK6/MAPK4 signaling
Drugs			Trifluoperazine Copper
Diseases
GWAS			Blood protein levels ( 29875488) Pulse pressure ( 30578418)
Interacting Genes		13 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE HDAC6 LINC01554 REL S100A4 SEPTIN10 SEPTIN11 SEPTIN5 SEPTIN9	28 interacting genes: ACTA1 ANXA2 BAG6 CCN3 CEP20 EGFR FCGR3A HSPB1 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 PPFIBP1 RHOU S100A1 S100B S100P SEPTIN2 SEPTIN6 SEPTIN7 SMAD3 SRPK2 TP53 TPM2 TPM3 UNC119
Entrez ID		989	6275
HPRD ID		04398	15914
Ensembl ID		ENSG00000122545	ENSG00000196154
Uniprot IDs		A0A023T695 A8K3D0 B4DNE4 G3V1Q4 Q16181	P26447
PDB IDs		2QAG 3T5D 3TW4 6N0B 6N12 6UQQ	1M31 2LNK 2MRD 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4CFQ 4CFR 4ETO 4HSZ 5LPU 6T58
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?