KNTC1 and ZWILCH

Data Source:
HPRD (in vitro, in vivo)

		KNTC1	ZWILCH
Description		kinetochore associated 1	zwilch kinetochore protein
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Pole Nucleus Kinetochore Microtubule Cytosol Plasma Membrane Actin Cytoskeleton RZZ Complex	Kinetochore Condensed Chromosome Kinetochore Cytosol RZZ Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Cell Division Protein-containing Complex Assembly	Protein Localization To Kinetochore Cell Division Signal Transduction Involved In Mitotic Cell Cycle Checkpoint
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Hand grip strength ( 29691431) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494) Menopause (age at onset) ( 26414677)	Body mass index ( 29273807)
Interacting Genes		2 interacting genes: PIAS4 ZWILCH	2 interacting genes: KNTC1 ZW10
Entrez ID		9735	55055
HPRD ID		09561	07640
Ensembl ID		ENSG00000184445	ENSG00000174442
Uniprot IDs		P50748	A8K4T3 Q9H900
PDB IDs			3IF8
Enriched GO Terms of Interacting Partners?
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