KNTC1 and MPHOSPH9

Data Source:
HPRD (in vivo)

		KNTC1	MPHOSPH9
Description		kinetochore associated 1	M-phase phosphoprotein 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Pole Nucleus Kinetochore Microtubule Cytosol Plasma Membrane Actin Cytoskeleton RZZ Complex	Golgi Membrane Golgi Apparatus Centriole Membrane
	Molecular Function	Protein Binding
	Biological Process	Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Cell Division Protein-containing Complex Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Hand grip strength ( 29691431) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 32888494) Menopause (age at onset) ( 26414677)	Albumin-globulin ratio ( 29403010) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Intelligence (MTAG) ( 29326435) Multiple sclerosis ( 19525953) Plasma anti-thyroglobulin levels ( 29678681) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 24509480 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Venous thromboembolism ( 31420334)
Interacting Genes		2 interacting genes: PIAS4 ZWILCH	3 interacting genes: SVIL YWHAG YWHAZ
Entrez ID		9735	10198
HPRD ID		09561	12022
Ensembl ID		ENSG00000184445	ENSG00000051825
Uniprot IDs		P50748	Q99550
PDB IDs
Enriched GO Terms of Interacting Partners?
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