RAB11FIP3 and IFT140

Data Source:
BioGRID (affinity chromatography technology)

		RAB11FIP3	IFT140
Description		RAB11 family interacting protein 3	intraflagellar transport 140
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip
	Molecular Function	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding	Molecular_function Protein Binding
	Biological Process	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development
Pathways		VxPx cargo-targeting to cilium	Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)	Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)
Interacting Genes		9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34	5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2
Entrez ID		9727	9742
HPRD ID		18521	11093
Ensembl ID		ENSG00000090565	ENSG00000187535
Uniprot IDs		O75154	Q96RY7
PDB IDs		2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?
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