RIMS2 and RAB3C

Data Source:
HPRD (in vitro)

		RIMS2	RAB3C
Description		regulating synaptic membrane exocytosis 2	RAB3C, member RAS oncogene family
Image			No pdb structure
GO Annotations	Cellular Component	Presynaptic Membrane Cell Projection Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Extracellular Exosome	Endosome Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Ion Channel Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Gene Expression Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Positive Regulation Of Synaptic Transmission Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Excitatory Postsynaptic Potential	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Protein Localization To Plasma Membrane
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089)	Breast cancer ( 29059683 23535729) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		12 interacting genes: ABCA1 CACNA1S RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH	5 interacting genes: FKBP2 RABIF RIMS2 RPH3AL VRTN
Entrez ID		9699	115827
HPRD ID		09436	06704
Ensembl ID		ENSG00000176406	ENSG00000152932
Uniprot IDs		Q9UQ26	Q96E17
PDB IDs		1V27 1WFG
Enriched GO Terms of Interacting Partners?
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