CD69 and ATP6V0C

Data Source:
BioGRID (two hybrid)

		CD69	ATP6V0C
Description		CD69 molecule	ATPase H+ transporting V0 subunit c
Image			No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane External Side Of Plasma Membrane Protein-containing Complex	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding Identical Protein Binding	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process		Insulin Receptor Signaling Pathway ATP Synthesis Coupled Proton Transport Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS		Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Medication use (thyroid preparations) ( 31015401) Monocyte count ( 32888494) Multiple sclerosis ( 24076602) Neutrophil percentage of white cells ( 32888494 27863252) Type 1 diabetes ( 25751624 19430480) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: ATP6V0C BRICD5 CLDN1 EBP MAL NINJ2 PMP22 RPRM SLC35B2 SMARCB1 STRIT1 TMEM190 TSPO2 UPK1B	53 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12
Entrez ID		969	527
HPRD ID		00119	00162
Ensembl ID		ENSG00000110848	ENSG00000185883
Uniprot IDs		Q07108 Q53ZX0	P27449
PDB IDs		1E87 1E8I 1FM5 3CCK 3HUP
Enriched GO Terms of Interacting Partners?
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