SEC24C and MIA2

Data Source:
BioGRID (two hybrid)

		SEC24C	MIA2
Description		SEC24 homolog C, COPII coat complex component	MIA SH3 domain ER export factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Endoplasmic Reticulum Exit Site
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating COPII-coated Vesicle Cargo Loading	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Secretion Vesicle Cargo Loading
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Cargo concentration in the ER
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	13 interacting genes: CCHCR1 CEP57 DGCR6 EMILIN1 GRB2 MAGEB18 PSMA3 RASAL2 SEC23A SEC24C SS18L1 TLE5 TTC23L
Entrez ID		9632	4253
HPRD ID		06217	03680
Ensembl ID		ENSG00000176986	ENSG00000150527
Uniprot IDs		A0A024QZM6 P53992	Q4G155 Q59FD2 Q96PC5
PDB IDs		3EH2
Enriched GO Terms of Interacting Partners?
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