PITPNM1 and PRKRA

Data Source:
HPRD (two hybrid)

		PITPNM1	PRKRA
Description		phosphatidylinositol transfer protein membrane associated 1	protein activator of interferon induced protein kinase EIF2AK2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Membrane Midbody Cleavage Furrow Golgi Cisterna Membrane Intracellular Membrane-bounded Organelle Cell Body	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex
	Molecular Function	Calcium Ion Binding Protein Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Receptor Tyrosine Kinase Binding Phosphatidylcholine Binding Phosphatidylinositol Binding Phosphatidic Acid Binding	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Brain Development Phototransduction Protein Transport Phospholipid Transport Intermembrane Lipid Transfer	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus MiRNA Metabolic Process Viral Process Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Synthesis of PI	MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases			Primary torsion dystonia (PTD)
GWAS		Refractive error ( 32231278)	Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		5 interacting genes: CDK1 PLK1 PTK2B RHOA TFCP2	28 interacting genes: ADARB1 AGO2 CEBPZ CEP126 COPS6 DICER1 EHHADH EIF2AK2 GDF9 LNX1 LYAR NKRF PIAS2 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746
Entrez ID		9600	8575
HPRD ID		07497	04573
Ensembl ID		ENSG00000110697	ENSG00000180228
Uniprot IDs		A0A024R5I7 B2R787 O00562	B4DJC7 O75569
PDB IDs			2DIX
Enriched GO Terms of Interacting Partners?
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