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PRKRA
Description
protein activator of interferon induced protein kinase EIF2AK2
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Perinuclear Region Of Cytoplasm
RISC-loading Complex
Molecular Function
RNA Binding
Double-stranded RNA Binding
Protein Binding
Enzyme Activator Activity
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
Pre-miRNA Binding
Biological Process
Protein Phosphorylation
Immune Response
Negative Regulation Of Cell Population Proliferation
Response To Virus
MiRNA Metabolic Process
Viral Process
Production Of SiRNA Involved In RNA Interference
Pre-miRNA Processing
Cellular Response To Oxidative Stress
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Outer Ear Morphogenesis
Middle Ear Morphogenesis
Skeletal System Morphogenesis
Regulation Of Catalytic Activity
Protein Stabilization
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Inflammatory skin disease (
25574825
)
Multiple sclerosis (OCB status) (
23472185
)
Rapid functional decline in sporadic amyotrophic lateral sclerosis (
26746183
)
Novel Interacting Genes
6 novel interacting genes:
CAT
CLASP1
FZD7
HEYL
PITPNM1
PLEKHA3
Interacting Genes
28 interacting genes:
ADARB1
AGO2
CEBPZ
CEP126
COPS6
DICER1
EHHADH
EIF2AK2
GDF9
LNX1
LYAR
NKRF
PIAS2
POLR2G
RABEPK
RB1
SETDB1
SHC1
SNX5
STAU1
STRBP
TARBP2
TIRAP
TP53
ZFP28
ZMAT3
ZMAT4
ZNF746
Entrez ID
8575
HPRD ID
04573
Ensembl ID
ENSG00000180228
Uniprot IDs
B4DJC7
O75569
PDB IDs
2DIX
Enriched GO Terms of Interacting Partners
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