BAG5 and CIRBP

Data Source:
BioGRID (two hybrid)

		BAG5	CIRBP
Description		BAG cochaperone 5	cold inducible RNA binding protein
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Repressor Activity Small Ribosomal Subunit RRNA Binding
	Biological Process	Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway	Response To Cold Response To UV Negative Regulation Of Translation Stress Granule Assembly Positive Regulation Of Translation Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)	Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		19 interacting genes: BANP CDCA7L CIRBP DES EFEMP1 FAM118B GOLGA6A HSPA4 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SNCA STUB1 THAP1 TP53 TRIM27	19 interacting genes: APP ATXN1 BAG5 CSNK2A1 FBXO7 HNRNPA0 HNRNPK IL7R KHDRBS1 KHDRBS2 LNX1 PRMT1 PRNP RBMX RBMY1A1 RBMY1F SNRPA SRF SRSF3
Entrez ID		9529	1153
HPRD ID		04862	08375
Ensembl ID		ENSG00000166170	ENSG00000099622
Uniprot IDs		A0A024R6M6 Q9UL15	D6W5Y5 K7EPM4 K7EQR7 Q14011 Q53XX5
PDB IDs		2D9D 3A8Y	1X5S 5TBX
Enriched GO Terms of Interacting Partners?
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