GOSR1 and NSF

Data Source:
HPRD (in vivo)

		GOSR1	NSF
Description		golgi SNAP receptor complex member 1	N-ethylmaleimide sensitive factor, vesicle fusing ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Golgi Medial Cisterna Cis-Golgi Network Cytosol Membrane Integral Component Of Membrane Transport Vesicle SNARE Complex	Golgi Membrane Lysosomal Membrane Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft
	Molecular Function	SNAP Receptor Activity	SNARE Binding Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Protein Kinase Binding PDZ Domain Binding Small GTPase Binding Ionotropic Glutamate Receptor Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Protein Transport Retrograde Transport, Endosome To Golgi Regulation Of Vesicle Targeting, To, From Or Within Golgi	Positive Regulation Of Receptor Recycling Potassium Ion Transport Intracellular Protein Transport Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Exocytosis SNARE Complex Disassembly Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Golgi Vesicle Docking
Pathways		COPI-mediated anterograde transport Intra-Golgi traffic	COPII-mediated vesicle transport Trafficking of GluR2-containing AMPA receptors COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs			1-Ethyl-Pyrrolidine-2,5-Dione
Diseases
GWAS			Alcohol use disorder (total score) ( 30336701) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (global PC1) ( 32198502) General factor of neuroticism ( 30867560) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 30054594) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Parkinson's disease ( 19915575 21812969) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Reaction time ( 29844566) Refractive error ( 32231278) Sense of smell ( 26632684) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		9 interacting genes: APP EBI3 GABARAPL2 GPR182 NAPA NSF SNAP25 STX5 USO1	28 interacting genes: ARRB1 ASPSCR1 CD28 CEP126 DRD2 EIF3E ERG28 ESR1 FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 LUC7L2 MEOX2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA
Entrez ID		9527	4905
HPRD ID		04936	03380
Ensembl ID		ENSG00000108587	ENSG00000073969
Uniprot IDs		E9PCW1 O95249	A0A384MTI6 P46459
PDB IDs			6KZQ
Enriched GO Terms of Interacting Partners?
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