ADAMTS1 and FAM32A

Data Source:
BioGRID (genetic interference)

		ADAMTS1	FAM32A
Description		ADAM metallopeptidase with thrombospondin type 1 motif 1	family with sequence similarity 32 member A
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GO Annotations	Cellular Component	Basement Membrane Extracellular Matrix Cytoplasmic Vesicle Collagen-containing Extracellular Matrix	Nucleoplasm Nucleolus
	Molecular Function	Metalloendopeptidase Activity Protein Binding Heparin Binding Metallopeptidase Activity Zinc Ion Binding	RNA Binding Protein Binding
	Biological Process	Ovulation From Ovarian Follicle Kidney Development Proteolysis Integrin-mediated Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Angiogenesis Extracellular Matrix Organization Heart Trabecula Formation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration	Apoptotic Process Cell Cycle Biological_process
Pathways		Degradation of the extracellular matrix Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Blood protein levels ( 28240269) Cerebrospinal fluid neurofilament light levels ( 31930058) Health literacy ( 31250787) Metabolite levels ( 23823483)
Interacting Genes		7 interacting genes: A2M ACAN FURIN KRT40 KRTAP10-8 VCAN VEGFA	2 interacting genes: APP NSFL1C
Entrez ID		9510	26017
HPRD ID		05530	13305
Ensembl ID		ENSG00000154734	ENSG00000105058
Uniprot IDs		B2RB33 Q9UHI8	A0A024R7I4 Q9Y421
PDB IDs		2JIH 2V4B 3Q2G 3Q2H	6QDV
Enriched GO Terms of Interacting Partners?
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