MED7 and RBFOX2

Data Source:
BioGRID (two hybrid)

		MED7	RBFOX2
Description		mediator complex subunit 7	RNA binding fox-1 homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleoplasm Transcription Regulator Complex Mediator Complex Nuclear Body	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding Ubiquitin Protein Ligase Activity	Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Population Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	FGFR2 alternative splicing
Drugs
Diseases
GWAS		Medication use (thyroid preparations) ( 31015401)	Body size at age 10 ( 32376654) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reading disability or specific language impairment (pleiotropy) ( 25065397) Red cell distribution width ( 32888494) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		23 interacting genes: CAB39 CTDP1 DNMT3L ESR1 ESR2 HAUS1 HGS HNF4A IKBKG LZTR1 MED31 MED8 MED9 PCBD2 PML RBFOX2 RELA RHOXF2 SREBF1 TRIM15 TRIM29 UBE2I ZSCAN1	120 interacting genes: APH1A ATN1 ATXN1 ATXN1L BOLL C1orf94 CAMK2A CAMK2B CHAF1A CHERP CLASP2 DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 FAM168B GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH1 HNRNPH2 HNRNPK KHDRBS1 KRTAP6-2 MAGED1 MAPK1IP1L MED7 MIR1-1 MIR106A MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR9-1 MIR9-2 MIR9-3 MIR93 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NAF1 NR2E3 OXER1 PCBP1 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBFOX3 RBM22 RBM23 RBM42 RBPMS RBPMS2 RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC SPOP TEX37 TOLLIP U2AF2 UBQLN2 VAC14 ZNF137P
Entrez ID		9443	23543
HPRD ID		05439	15231
Ensembl ID		ENSG00000155868	ENSG00000100320
Uniprot IDs		O43513 Q6IAZ5	O43251
PDB IDs			2CQ3
Enriched GO Terms of Interacting Partners?
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