TNFRSF8 and HPCA

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		TNFRSF8	HPCA
Description		TNF receptor superfamily member 8	hippocalcin
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane Extracellular Exosome	Cytoplasm Cytosol Extrinsic Component Of Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Glutamatergic Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Cell Population Proliferation Positive Regulation Of TRAIL Production Positive Regulation Of Tumor Necrosis Factor Production Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Apoptotic Process Cellular Response To Mechanical Stimulus	Brain Development Calcium-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Activation Of Phospholipase D Activity Positive Regulation Of Adenylate Cyclase Activity Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Cellular Response To Monosodium Glutamate Response To Aroclor 1254
Pathways		TNFs bind their physiological receptors
Drugs		XmAb 2513 Brentuximab vedotin
Diseases
GWAS		Asthma ( 31959851 32296059) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Mosquito bite size ( 28199695) Neutrophil percentage of granulocytes ( 27863252) Sum eosinophil basophil counts ( 27863252) Tuberculosis ( 29036319)
Interacting Genes		7 interacting genes: ALK TDP2 TNFSF8 TRAF1 TRAF2 TRAF3 TRAF5	16 interacting genes: C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2
Entrez ID		943	3208
HPRD ID		01074	00811
Ensembl ID		ENSG00000120949	ENSG00000121905
Uniprot IDs		A5D8T4 P28908	P84074
PDB IDs		1D01	5G4P 5G58 5M6C
Enriched GO Terms of Interacting Partners?
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