CAPZA3 and CAPZA2

Data Source:
HPRD (in vitro)

		CAPZA3	CAPZA2
Description		capping actin protein of muscle Z-line subunit alpha 3	capping actin protein of muscle Z-line subunit alpha 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol F-actin Capping Protein Complex Membrane Cortical Cytoskeleton Sperm Head	Extracellular Region Cytosol Brush Border F-actin Capping Protein Complex Actin Cytoskeleton Membrane Cortical Cytoskeleton Extracellular Exosome
	Molecular Function	Actin Filament Binding	Protein Binding Actin Filament Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Actin Filament Organization Cytoplasm Organization Spermatid Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Actin Cytoskeleton Organization Barbed-end Actin Filament Capping	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Blood Coagulation Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Actin Cytoskeleton Organization Innate Immune Response Barbed-end Actin Filament Capping Protein-containing Complex Assembly
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Advanced glycosylation endproduct receptor signaling Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Personality dimensions ( 23903073)	Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 27841878) Triglyceride levels ( 32203549 32154731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		2 interacting genes: ACTG1 CAPZA2	3 interacting genes: CAPZA3 HSPB2 RBBP6
Entrez ID		93661	830
HPRD ID		12282	11871
Ensembl ID		ENSG00000177938	ENSG00000198898
Uniprot IDs		A0A140VKF6 Q96KX2	A4D0V4 P47755
PDB IDs
Enriched GO Terms of Interacting Partners?
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