PPIG and KCTD6

Data Source:
BioGRID (two hybrid)

		PPIG	KCTD6
Description		peptidylprolyl isomerase G	potassium channel tetramerization domain containing 6
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Matrix Nuclear Speck Intracellular Membrane-bounded Organelle	Cytosol M Band
	Molecular Function	RNA Binding Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding	Protein Binding Ankyrin Binding Identical Protein Binding Cullin Family Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding RNA Splicing	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Growth Post-translational Protein Modification Negative Regulation Of Smoothened Signaling Pathway Protein Homooligomerization
Pathways			RUNX1 regulates estrogen receptor mediated transcription Neddylation Estrogen-dependent gene expression Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Proline
Diseases
GWAS			Hepcidin/transferrin saturation ratio ( 27846281) Refractive error ( 32231278) Systemic lupus erythematosus ( 28714469) vWF levels ( 30586737)
Interacting Genes		27 interacting genes: BEND7 CACNA1A CEP70 CLK1 DAB1 DACH1 FHL3 KCTD6 LGALS3 NKAP PCBP1 PNMA2 PNN POLR2A PPCDC PRPF38A PRPF40A RBM39 SLU7 SMN1 SMN2 SP1 TFCP2 THAP1 TRIM54 YWHAG ZCCHC10	28 interacting genes: ACTN1 ACTN3 ANK1 BAG4 C8orf33 CDC23 CTNND1 CUL3 EHHADH ERBB2 FAM124B GOLGA8EP GOLGA8F GRB7 GSDMD LNX1 MOS NTAQ1 PICK1 PPIG PRPF31 PSMA1 REL SDCBP TBC1D2 TCEANC TEPSIN ZCCHC10
Entrez ID		9360	200845
HPRD ID		12083	13769
Ensembl ID		ENSG00000138398	ENSG00000168301
Uniprot IDs		Q13427	Q8NC69
PDB IDs		2GW2 2WFI 2WFJ 5YZG
Enriched GO Terms of Interacting Partners?
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