TAOK2 and RTRAF

Data Source:
BioGRID (affinity chromatography technology)

		TAOK2	RTRAF
Description		TAO kinase 2	RNA transcription, translation and transport factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm TRNA-splicing Ligase Complex Mitotic Spindle
	Molecular Function	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity	RNA Polymerase II Complex Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Regulation Of Cell Growth Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Axonogenesis Regulation Of Cell Shape Cell Migration Actin Cytoskeleton Organization Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Neuron Projection Morphogenesis Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Negative Regulation Of Protein Kinase Activity Viral Process Positive Regulation Of Transcription By RNA Polymerase II RNA Transport
Pathways			tRNA processing in the nucleus
Drugs		Dexfosfoserine Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 31928498) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260) Triglyceride levels ( 32203549 32154731) Waist circumference ( 31928498)
Interacting Genes		13 interacting genes: CIDEB ELK1 KLHL12 KRTAP6-3 MAP2K3 MAP2K6 MAPRE3 MEGF10 RCHY1 TUBA1A TUBA4A TUBB USF1	6 interacting genes: DISC1 FAM98A GLP1R MTNR1A NIN PSORS1C2
Entrez ID		9344	51637
HPRD ID		18147	16615
Ensembl ID		ENSG00000149930	ENSG00000087302
Uniprot IDs		Q9UL54	Q549M8 Q9Y224
PDB IDs
Enriched GO Terms of Interacting Partners?
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