SHKBP1 and LXN

		SHKBP1	LXN
Description		SH3KBP1 binding protein 1	latexin
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GO Annotations	Cellular Component	Lysosome	Extracellular Space Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding
	Biological Process	Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Homooligomerization	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Pathways
Drugs
Diseases
GWAS		Carotid intima media thickness (mean) ( 31801372) Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216) Hemoglobin levels ( 32327693)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		10 interacting genes: CCNG1 COL7A1 CUL3 GRB2 LXN NR3C1 PIN1 PRPF3 SH3KBP1 YWHAG	25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679
Entrez ID		92799	56925
HPRD ID		15338	14327
Ensembl ID		ENSG00000160410	ENSG00000079257
Uniprot IDs		B3KVX8 Q8TBC3	Q9BS40
PDB IDs		4CRH	2BO9
Enriched GO Terms of Interacting Partners?
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