DRC1 and CENPO

Data Source:
BioGRID (affinity chromatography technology)

		DRC1	CENPO
Description		dynein regulatory complex subunit 1	centromere protein O
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Axonemal Dynein Complex Axoneme Motile Cilium	Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex
	Molecular Function		Protein Binding
	Biological Process	Regulation Of Cilium Movement Determination Of Left/right Symmetry Heart Development Cilium-dependent Cell Motility Axonemal Dynein Complex Assembly	CENP-A Containing Nucleosome Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)
Interacting Genes			7 interacting genes: CENPP CEP170P1 DCDC2 ERI3 FOS FOSB NECAB2
Entrez ID		92749	79172
HPRD ID		11312	14414
Ensembl ID		ENSG00000157856	ENSG00000138092
Uniprot IDs		Q96MC2	Q9BU64
PDB IDs
Enriched GO Terms of Interacting Partners?
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