MFHAS1 and STK25

Data Source:
BioGRID (pull down)

		MFHAS1	STK25
Description		malignant fibrous histiocytoma amplified sequence 1	serine/threonine kinase 25
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Lysosome Cytoskeleton	Golgi Membrane Cytoplasm Golgi Apparatus Extracellular Exosome
	Molecular Function	Protein Binding GTP Binding Ubiquitin Protein Ligase Binding Protein Phosphatase 2A Binding	Protein Kinase Activity Protein Binding ATP Binding Protein Homodimerization Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Inflammatory Response Erythrocyte Differentiation Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Protein Dephosphorylation Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of JNK Cascade Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of P38MAPK Cascade	Protein Phosphorylation Response To Oxidative Stress Establishment Or Maintenance Of Cell Polarity Signal Transduction Positive Regulation Of Stress-activated MAPK Cascade Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Protein Autophosphorylation Positive Regulation Of Axonogenesis Golgi Localization Establishment Of Golgi Localization Golgi Reassembly
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Adventurousness ( 30643258) Age at first sexual intercourse ( 27089180) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease ( 30804561) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Cooked vegetable consumption ( 32066663) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Metabolite levels ( 23823483) Mood instability ( 29187730) Neuroticism ( 29255261) Processed meat consumption ( 32066663) Refractive error ( 32231278) Skin aging (microtopography measurement) ( 28502801) Systemic lupus erythematosus ( 28714469) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Medication use (thyroid preparations) ( 31015401) Prostate cancer ( 23535732) Vitiligo ( 27723757)
Interacting Genes		88 interacting genes: ABLIM1 AGFG1 AHCYL1 AHDC1 ANKRD13A ANKRD13D ANKS4B APEX2 AURKB BAG2 CABP4 CALM1 CALML3 CALU CAPRIN1 CBLB CCDC149 CCDC43 CDC42EP3 CEBPZ CEP85 CETN3 CHGB CLK1 COPB2 CRTC2 CUEDC1 CYREN DDI1 DRC3 E2F4 EGLN2 ESRRG ETV5 FGF16 FGFR1 FOXN3 GAK GAS2L3 GPBP1L1 GSDMD GTSF1 HIC2 IFTAP KLHDC4 LIMA1 LIMK1 MAP3K4 MRGBP NEK1 NEK11 PDCL PGRMC2 PJA2 PMM1 POLA2 POLI PPARG PRKAG2 PSME3IP1 RASL11B RCN2 RHBDD1 ROR1 RPAP3 RTKN SELENOS SH2D2A SLC4A1AP SMTNL2 SNAI1 STK25 STN1 STUB1 SUPT4H1 TADA3 TAS2R60 TBC1D22B TOX2 TRAPPC2 TRIM22 TTC27 UBL7 VGLL4 VN1R1 WWTR1 ZFAND5 ZMYM5	16 interacting genes: APP CCNDBP1 CEP70 GOLGA2 GOLGA6L9 IHO1 IKBKG LRRK2 MFHAS1 MTDH NEDD4 PDCD10 TRIM27 UBE2D3 YWHAZ ZDHHC17
Entrez ID		9258	10494
HPRD ID		12010	03770
Ensembl ID		ENSG00000147324	ENSG00000115694
Uniprot IDs		Q9Y4C4	A0A024R4B2 A0A0S2Z4Y2 B3KRS6 B4DMA5 B4DVS7 B4E185 O00506 Q96BA2
PDB IDs			2XIK 3W8H 4NZW
Enriched GO Terms of Interacting Partners?
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