DAPL1 and FNDC3B

Data Source:
BioGRID (two hybrid)

		DAPL1	FNDC3B
Description		death associated protein like 1	fibronectin type III domain containing 3B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Integral Component Of Membrane
	Molecular Function	Protein Binding Death Domain Binding	RNA Binding
	Biological Process	Negative Regulation Of Autophagy Cell Differentiation Cellular Response To Amino Acid Starvation Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Obesity-related traits ( 23251661)	Central corneal thickness ( 32528159 31798171 29760442 30894546) Corneal hysteresis ( 30894546) Corneal resistance factor ( 31246245 30894546) Corneal structure ( 23291589) Coronary artery disease ( 29212778 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Glycated hemoglobin levels ( 28898252) Heart rate ( 23583979) Height ( 28552196 25282103 25429064 23563607 31562340) Hip circumference adjusted for BMI ( 28552196 25673412) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998 25173106 31798171 29785010 30054594 28073927 29235454) Intraocular pressure (Goldman correlated) ( 30894546) Mean corpuscular hemoglobin ( 32888494) Parkinson's disease ( 26227905) PR interval ( 32439900) Pulse pressure ( 30224653) Red cell distribution width ( 32888494 27863252 28957414) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triptolide cytotoxicity ( 26121980) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for BMI in smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		7 interacting genes: FHL2 FNDC3B LSM1 TRIM55 TRIM63 TSR2 ZIC1	52 interacting genes: ABHD11 ABHD8 ADGRF5 BBS2 BICRAL BRWD1 C10orf55 C10orf82 C19orf54 C22orf15 CAMK2D CAPN3 CEMP1 DAPL1 DUSP10 ERCC6 GAS2L3 HAPLN2 KLHDC7B KRTAP11-1 L3MBTL3 MBD3L1 MCCD1 MVP NDUFAB1 PIK3R4 POGZ POU6F2 PRKAA2 REL RUSC1 SPSB2 SRARP STPG4 SUOX TEKT5 TEPSIN TESMIN TEX43 TEX48 TIAM1 TOX4 TRAF2 TRIM35 TRIM42 TRIP13 TTN UBAP2 USP54 VAC14 YPEL3 ZMYND19
Entrez ID		92196	64778
HPRD ID		18709	10943
Ensembl ID		ENSG00000163331	ENSG00000075420
Uniprot IDs		A0PJW8 M1E9T5	Q53EP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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