RIPPLY1 and USP6

Data Source:
BioGRID (two hybrid)

		RIPPLY1	USP6
Description		ripply transcriptional repressor 1	ubiquitin specific peptidase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Lysosome Plasma Membrane Recycling Endosome
	Molecular Function	Protein Binding	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Somite Specification Embryonic Pattern Specification Somite Rostral/caudal Axis Specification Negative Regulation Of Transcription, DNA-templated	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Intracellular Protein Transport Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Vesicle-mediated Transport Activation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)	PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		45 interacting genes: AVPI1 BEND7 CFAP58 CTNNA3 DCAF15 DIRAS2 FHL2 GRAPL GRHL3 H3-4 HAND2 HDAC7 IRAK1BP1 KRT34 MCCD1 MDFI MED19 MEOX2 NDUFB7 PATZ1 PBX4 PFDN5 PLAGL2 PRR20A PRR20B PRR20C PRR20D PRR20E PTTG2 RBPMS REL RHOH RNF144B SAPCD1 THAP1 TLE5 TRAF1 TRAF2 TRAF3 USP6 VAC14 VGLL1 ZMYND12 ZNF620 ZNF784	18 interacting genes: ANKRD11 ANKRD44 APP ATXN7L3 CABP2 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 RIPPLY1 TFIP11 UBC ZNF76
Entrez ID		92129	9098
HPRD ID			06827
Ensembl ID		ENSG00000147223	ENSG00000129204
Uniprot IDs		Q0D2K3	P35125
PDB IDs
Enriched GO Terms of Interacting Partners?
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