DGKI and CHCHD3

Data Source:
BioGRID (two hybrid)

		DGKI	CHCHD3
Description		diacylglycerol kinase iota	coiled-coil-helix-coiled-coil-helix domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Axon Synaptic Vesicle Membrane Protein-containing Complex Dendritic Spine Synapse Synaptic Membrane	SAM Complex Nucleus Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome MIB Complex
	Molecular Function	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Platelet Activation Intracellular Signal Transduction Diacylglycerol Metabolic Process Lipid Phosphorylation Regulation Of Synaptic Transmission, Glutamatergic	Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways		Effects of PIP2 hydrolysis	Mitochondrial protein import Cristae formation
Drugs		alpha-Tocopherol succinate
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) AIDS progression ( 21502085) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26865924) Brain morphology (MOSTest) ( 32665545) Cognitive decline (age-related) ( 24468470) General risk tolerance (MTAG) ( 30643258) Lean body mass ( 28552196) Schizophrenia ( 28991256 25056061 29483656 30285260) Subcortical volume (MOSTest) ( 32665545) Testosterone levels in polycystic ovary syndrome ( 26284813)	Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		1 interacting genes: VHL	37 interacting genes: AMOTL2 ANKS1A ARMC7 BLZF1 C2CD6 CALCOCO2 CBY2 CCDC33 CCDC85B CEP72 CYSRT1 EFHC1 ENKD1 FANCL GMCL2 GOLGA2 KANK2 KRT40 KRTAP4-12 LMO1 LZTS2 NBPF19 NOTCH2NLA NTAQ1 NUDT3 NUTF2 NUTM1 PDE4DIP PPP1CB RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		9162	54927
HPRD ID		07238	13044
Ensembl ID		ENSG00000157680	ENSG00000106554
Uniprot IDs		E7EWQ4 E9PFX6 O75912 Q59GE2	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs
Enriched GO Terms of Interacting Partners?
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