RASL10B and NDUFS3

Data Source:
BioGRID (two hybrid)

		RASL10B	NDUFS3
Description		RAS like family 10 member B	NADH:ubiquinone oxidoreductase core subunit S3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Mitochondrion Mitochondrial Respiratory Chain Complex I Mitochondrial Matrix Nuclear Body Mitochondrial Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	NADH Dehydrogenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Transfer Activity
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Atrial Natriuretic Peptide Signal Transduction Positive Regulation Of Peptide Hormone Secretion	Mitochondrial Electron Transport, NADH To Ubiquinone Substantia Nigra Development Negative Regulation Of Cell Growth Mitochondrial Respiratory Chain Complex I Assembly Reactive Oxygen Species Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321)	Adult body size ( 32376654) Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Bipolar disorder ( 31043756) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 20935630) Body size at age 10 ( 32376654) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Height ( 28552196) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mood instability ( 31168069) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)
Interacting Genes		11 interacting genes: AKT1 APP BAG4 FGFR2 FGFR4 MAPK9 NDUFS3 NEDD4L PARP1 PAX2 TSG101	4 interacting genes: GZMA NDUFA5 RASL10B TMEM11
Entrez ID		91608	4722
HPRD ID		15215	10355
Ensembl ID		ENSG00000270885	ENSG00000213619
Uniprot IDs		Q96S79	O75489
PDB IDs			5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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