PDLIM1 and AGK

Data Source:
HPRD (two hybrid)

		PDLIM1	AGK
Description		PDZ and LIM domain 1	acylglycerol kinase
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GO Annotations	Cellular Component	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion	Lipid Kinase Activity Ceramide Kinase Activity NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding D-erythro-sphingosine Kinase Activity Acylglycerol Kinase Activity Dihydroceramide Kinase Activity
	Biological Process	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion	Sphingolipid Metabolic Process Phosphorylation Protein Insertion Into Mitochondrial Inner Membrane Glycerophospholipid Biosynthetic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Lipid Phosphorylation
Pathways			Glycerophospholipid biosynthesis Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)	Mood disorder and prion disease ( 25897833)
Interacting Genes		14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM	3 interacting genes: HCK PDLIM1 SNX4
Entrez ID		9124	55750
HPRD ID		09326	08554
Ensembl ID		ENSG00000107438	ENSG00000006530
Uniprot IDs		O00151 V9HW92	A4D1U5 Q53H12
PDB IDs		1X62 2PKT	7CGP
Enriched GO Terms of Interacting Partners?
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