AP5B1 and PDLIM7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		AP5B1	PDLIM7
Description		adaptor related protein complex 5 subunit beta 1	PDZ and LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane AP-type Membrane Coat Adaptor Complex	Stress Fiber Ruffle Nucleoplasm Cytosol Adherens Junction Focal Adhesion Actin Cytoskeleton Z Disc Filamentous Actin
	Molecular Function	Protein Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Protein Transport Endosomal Transport	Ossification Receptor-mediated Endocytosis Axon Guidance Heart Development Actin Cytoskeleton Organization Positive Regulation Of Osteoblast Differentiation Muscle Structure Development
Pathways			RET signaling
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31361310 30929738 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Atopic march ( 26542096) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Creatinine levels ( 29403010) Eczema ( 31361310) Glomerular filtration rate (creatinine) ( 26831199) Parental longevity (combined parental attained age, Martingale residuals) ( 29227965) Psoriasis ( 25854761) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: CALCOCO2 CAMK2B KCNRG NIF3L1 PDLIM7	62 interacting genes: ABI2 AP5B1 BAG3 BSG CATSPER1 CCDC185 DDX6 DGCR6 DNER ENKD1 FAM214B FAM71C FAM90A1 FNDC11 FRS3 GEM GFAP GPATCH2L HEY2 HNRNPD HNRNPF HSF2BP HSPB7 IL16 IQGAP1 KANK2 MDM2 NUDT10 OTUD6A PAK5 PARVG PCBP1 PHF1 PIN1 PLEKHN1 PRKCA PRKCB PRKCZ PRKD2 PSMF1 RASGEF1B RET RPP25 SCNM1 SH2B2 SH3BP2 SLAIN1 SMURF1 SPP1 TCF19 TNPO2 TP53 TPM2 TRAF2 TRAF3 TSG101 TSGA10IP UBE2I UBQLN4 WWP2 ZMYND11 ZNF165
Entrez ID		91056	9260
HPRD ID		13223	10436
Ensembl ID		ENSG00000254470	ENSG00000196923
Uniprot IDs		Q2VPB7	Q9NR12
PDB IDs			2Q3G
Enriched GO Terms of Interacting Partners?
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