PIGQ and PIGC

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		PIGQ	PIGC
Description		phosphatidylinositol glycan anchor biosynthesis class Q	phosphatidylinositol glycan anchor biosynthesis class C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Catalytic Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	Carbohydrate Metabolic Process GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane	GPI Anchor Biosynthetic Process Preassembly Of GPI Anchor In ER Membrane
Pathways			Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Disc degeneration (lumbar) ( 22993228) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Daytime sleep phenotypes ( 27126917) Hemoglobin levels ( 32327693) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		4 interacting genes: PIGA PIGC PIGH SMAD1	4 interacting genes: DPM2 KLF10 PIGQ ZHX1
Entrez ID		9091	5279
HPRD ID		09307	03433
Ensembl ID		ENSG00000007541	ENSG00000135845
Uniprot IDs		B2RAU6 Q9BRB3	Q92535
PDB IDs
Enriched GO Terms of Interacting Partners?
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