SLC7A6 and DOLK

Data Source:
BioGRID (two hybrid)

		SLC7A6	DOLK
Description		solute carrier family 7 member 6	dolichol kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity Antiporter Activity	Dolichol Kinase Activity Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport L-amino Acid Transport Ornithine Transport Leukocyte Migration L-alpha-amino Acid Transmembrane Transport Basic Amino Acid Transmembrane Transport	Dolichyl Diphosphate Biosynthetic Process Phosphorylation Dolichyl Monophosphate Biosynthetic Process
Pathways		Basigin interactions Amino acid transport across the plasma membrane	Synthesis of Dolichyl-phosphate Defective DOLK causes DOLK-CDG (CDG-1m)
Drugs
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Body mass index ( 28552196) Estimated glomerular filtration rate ( 31152163 30604766) Glomerular filtration rate (creatinine) ( 28452372 26831199) Metabolic traits ( 21886157) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260) Serum metabolite levels ( 23093944)
Interacting Genes		1 interacting genes: DOLK	22 interacting genes: APPBP2 CD79A CHODL CREB3 CREB3L1 EDA FAM209A FNDC9 GALNT8 GJA8 GPX8 KCNA1 KCNA10 KCNA3 KCNA6 LRRC4C SLC7A6 SYNPR TMEM45B TMEM80 UBQLN1 VSIR
Entrez ID		9057	22845
HPRD ID		12031	15525
Ensembl ID		ENSG00000103064	ENSG00000175283
Uniprot IDs		A0A024R719 Q92536	A0A0S2Z597 Q9UPQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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