DOK2 and DOK3

Data Source:
BioGRID (two hybrid)

		DOK2	DOK3
Description		docking protein 2	docking protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Plasma Membrane Secretory Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Protein Binding	Protein Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ras Protein Signal Transduction Axon Guidance Viral Process Leukocyte Migration	Neutrophil Degranulation
Pathways		Tie2 Signaling RET signaling	Neutrophil degranulation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Entorhinal cortical thickness ( 21116278) Lymphocyte counts ( 32888494) Mean corpuscular volume ( 20139978) Mean platelet volume ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Neuropathic pain in type 2 diabetes ( 24974787) Neutrophil percentage of white cells ( 32888494) Pancreatic cancer ( 30206226) Platelet distribution width ( 32888494) Refractive error ( 32231278) Verbal declarative memory ( 25648963)	Coronary artery disease ( 29212778) Inflammatory bowel disease ( 23128233) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: ABL1 APPL1 CRK CRKL CSK DOK3 EGFR HCK IL4R INPP5D KIFBP LCK LYN NCK1 POT1 RASA1 RET SRC STAT3 TEK TXK YES1	31 interacting genes: A1CF ABL1 ANKS1A APPL1 APPL2 COX5B CRK CSK DOK1 DOK2 DOK5 DTX2 FYN GCM2 HOXA1 INPP5D LCK LYN MDFI PLEKHA3 PPIH PRKAB2 RBPMS RET RIN3 SHC3 SHE SPAG8 STAT3 TNS2 TRAF1
Entrez ID		9046	79930
HPRD ID		05411	16834
Ensembl ID		ENSG00000147443	ENSG00000146094
Uniprot IDs		B4DKQ6 O60496	A0A024R7M5 A0A6M4C8X9 D6RAM3 Q7L591
PDB IDs		2D9W 2DLW
Enriched GO Terms of Interacting Partners?
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