TICRR and CRTC3

Data Source:
BioGRID (affinity chromatography technology)

		TICRR	CRTC3
Description		TOPBP1 interacting checkpoint and replication regulator	CREB regulated transcription coactivator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Protein Binding	Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	DNA Replication DNA Repair Mitotic Cell Cycle Checkpoint Mitotic G2 DNA Damage Checkpoint Response To Ionizing Radiation Regulation Of DNA-dependent DNA Replication Initiation Mitotic DNA Replication Checkpoint	Viral Process Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis
Pathways			Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Resting oxygen saturation in chronic osbtructive pulmonary disease (pulse oxymetry) ( 24825563) Type 2 diabetes ( 31049640)	Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: APP TOPBP1	4 interacting genes: CA13 KLHL12 SIK2 YWHAG
Entrez ID		90381	64784
HPRD ID		11357	13384
Ensembl ID		ENSG00000140534	ENSG00000140577
Uniprot IDs		Q7Z2Z1	Q6UUV7 Q8TEF4
PDB IDs
Enriched GO Terms of Interacting Partners?
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