CCDC120 and SFI1

Data Source:
BioGRID (two hybrid)

		CCDC120	SFI1
Description		coiled-coil domain containing 120	SFI1 centrin binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Centriole Growth Cone Centriolar Subdistal Appendage	Centrosome Centriole Cytosol
	Molecular Function	Protein Binding	Protein Binding Phosphatase Binding
	Biological Process	Multicellular Organism Development Protein Localization Microtubule Anchoring At Centrosome	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Phosphatase Activity Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS			Age-related hearing impairment ( 24939585) Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Fish- and plant-related diet ( 32066663) Lymphocyte counts ( 32888494) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Type 2 diabetes ( 31118516)
Interacting Genes		106 interacting genes: AKAP8L ARID5A ATP23 BCAS2 BHLHB9 BLZF1 BRCA1 C1orf109 CADPS CALCOCO2 CCDC102B CCDC13 CCDC136 CCDC57 CCDC85B CDR2 CEP170P1 CEP55 CKS1B CNFN COG6 CTBP2 CYSRT1 CYTH1 CYTH2 CYTH3 CYTH4 DAZAP2 EFHC2 EIF3F FCHSD2 FOS FOSL1 FSD2 GOLGA2 GOLGA6L9 HNRNPH1 HOMER3 HOXA1 HSF2BP IFT88 IHO1 INTS11 KASH5 KRT15 KRT31 KRT34 KRT35 KRT38 KRT40 KRTAP13-3 KRTAP19-1 KRTAP6-1 KRTAP6-2 KRTAP6-3 LMNA LMNB2 LMO4 LZTS1 MAGED1 MDFI MED11 METTL27 MID2 MIIP MIPOL1 MKRN3 MRPL38 MTUS2 MYOG NCK2 NEK6 NOTO NXF1 PKP2 PLA2G10 PLAGL2 PLEKHG4 POU2AF1 PRDM6 RABEP1 RBPMS RERE RINT1 RUSC1 SFI1 SMARCB1 SORBS3 SPAG8 STX11 TFIP11 TLE5 TP53BP1 TRAF1 TRIM42 TRIM55 TRIM63 TRIP6 TSC1 TSGA10IP USHBP1 ZDHHC17 ZIM2 ZMAT5 ZNF648 ZRANB1	14 interacting genes: CCDC120 CCDC57 CETN2 CRX FAM131C GCSH GOLGA2 KRT19 LPXN MAD2L2 MDFI RADIL RBPMS SERTAD1
Entrez ID		90060	9814
HPRD ID		06595	11550
Ensembl ID		ENSG00000147144	ENSG00000198089
Uniprot IDs		Q96HB5	A8K8P3
PDB IDs			2K2I
Enriched GO Terms of Interacting Partners?
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