CCND3 and CRABP2

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		CCND3	CRABP2
Description		cyclin D3	cellular retinoic acid binding protein 2
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GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Membrane	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding	Retinoic Acid Binding Retinoid Binding Protein Binding Retinal Binding Retinol Binding Cyclin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Phosphorylation Signal Transduction T Cell Proliferation Regulation Of Cell Population Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Insulin Receptor Signaling Pathway Cell Division Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription, DNA-templated Signal Transduction Epidermis Development Embryonic Forelimb Morphogenesis Retinoic Acid Metabolic Process Positive Regulation Of Collateral Sprouting
Pathways		Transcriptional regulation of white adipocyte differentiation MAPK6/MAPK4 signaling Cyclin D associated events in G1 Regulation of RUNX1 Expression and Activity Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Signaling by Retinoic Acid
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Cardiometabolic and hematological traits ( 27668658) Crohn's disease ( 28067908) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549 28334899) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hematological parameters ( 19820697) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin ( 29403010 32888494 28453575 20139978 27863252 28017375 19862010) Mean corpuscular hemoglobin concentration ( 32888494 28017375) Mean corpuscular volume ( 23263863 29403010 32888494 28453575 20139978 27863252 28017375 19862010) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil count ( 21507922) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 29403010 32888494 20139978 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) White blood cell count ( 32888494)
Interacting Genes		56 interacting genes: AKAP8 APP AREG ATF5 ATP5F1C C14orf119 CASP2 CCDC13 CDK11B CDK14 CDK16 CDK18 CDK3 CDK4 CDK5 CDK6 CDKN1A CDKN1B CDKN2D CRABP2 DMRTB1 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS FHL3 GC HGS KIFC3 LSM3 MAF1 MAPK4 MAPK6 MCM10 MNS1 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL PSMC1 QKI RARA RB1 RBL2 RUNX1 SH3GLB2 SIL1 TEX11 TFIP11 TSG101 VDR	4 interacting genes: ACTN2 CCND3 FLAD1 KASH5
Entrez ID		896	1382
HPRD ID		00452	08353
Ensembl ID		ENSG00000112576	ENSG00000143320
Uniprot IDs		B3KP19 D6RI00 P30281 Q5T8J1	P29373
PDB IDs		3G33	1BLR 1BM5 1CBQ 1CBS 1XCA 2CBS 2FR3 2FRS 2FS6 2FS7 2G78 2G79 2G7B 3CBS 3CR6 3CWK 3D95 3D96 3D97 3F8A 3F9D 3FA6 3FA7 3FA8 3FA9 3FEK 3FEL 3FEN 3FEP 3I17 4I9R 4I9S 4M6S 4M7M 4QGV 4QGW 4QGX 4YBP 4YBU 4YCE 4YCH 4YDA 4YDB 4YFP 4YFQ 4YFR 4YGG 4YGH 4YGZ 4YH0 4YKM 4YKO 5HZQ 5OGB 6HKR 6MOP 6MOQ 6MOR 6MOV 6MOW 6MOX 6MPK 6MQI 6MQJ 6MQW 6MQX 6MQY 6MQZ 6MR0 6NNX 6NNY 6NOE
Enriched GO Terms of Interacting Partners?
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