EIF2B2 and TBCE

Data Source:
BioGRID (two hybrid)

		EIF2B2	TBCE
Description		eukaryotic translation initiation factor 2B subunit beta	tubulin folding cofactor E
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GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Cytoplasm Microtubule
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding	Protein Binding Alpha-tubulin Binding Chaperone Binding
	Biological Process	Ovarian Follicle Development Translational Initiation Regulation Of Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone Regulation Of Catalytic Activity T Cell Receptor Signaling Pathway	Microtubule Cytoskeleton Organization Protein Folding Tubulin Complex Assembly Post-chaperonin Tubulin Folding Pathway Mitotic Spindle Organization
Pathways		Recycling of eIF2:GDP	Post-chaperonin tubulin folding pathway
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)	Hypoparathyroidism-retardation-dysmorphism syndrome; Sanjad-Sakati syndrome Kenny-Caffey syndrome
GWAS		Coronary artery disease ( 33020668) Mood instability ( 29187730) Youthful appearance (self-reported) ( 32339537)	Adiposity ( 19557161) Blood protein levels ( 30072576) Household income (MTAG) ( 31844048)
Interacting Genes		12 interacting genes: APP C9orf72 CCT3 CSNK2A2 EIF2B1 EIF2B4 EIF2B5 EIF2S1 MRFAP1L1 NCK1 PCGF6 TET2	2 interacting genes: TBCD TUBA4A
Entrez ID		8892	6905
HPRD ID		05923	05381
Ensembl ID		ENSG00000119718	ENSG00000284770
Uniprot IDs		P49770 Q53XC2	A0A2R8Y6Q1 Q15813
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z	4ICU 4ICV
Enriched GO Terms of Interacting Partners?
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