CDC123 and ARID1A

Data Source:
BioGRID (affinity chromatography technology)

		CDC123	ARID1A
Description		cell division cycle 123	AT-rich interaction domain 1A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Chromatin Nucleus Nucleoplasm SWI/SNF Complex Brahma Complex NpBAF Complex NBAF Complex
	Molecular Function		DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding Nucleosome Binding
	Biological Process	Cell Cycle Arrest Positive Regulation Of Cell Population Proliferation Positive Regulation Of Translational Initiation Cell Division Eukaryotic Translation Initiation Factor 2 Complex Assembly	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Nucleosome Mobilization Glucocorticoid Receptor Signaling Pathway ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription
Pathways			RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Body mass index ( 28892062) Chronic obstructive pulmonary disease ( 30804561) Circulating leptin levels or type 2 diabetes ( 32341051) Coronary artery disease ( 33020668) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) FEV1 ( 30804560) Hemoglobin A1c levels ( 29403010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 28166213 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Peak expiratory flow ( 30804560) Pulmonary function ( 21946350) Pulmonary function (smoking interaction) ( 23284291) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Type 2 diabetes ( 22885922 18372903 24509480 30054458 26961502 20862305 29358691 30297969 26818947 31118516 22961080 32499647 30718926 28869590)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549 28869591) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolic syndrome ( 31589552) Monocyte percentage of white cells ( 27863252) Neutrophil count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Rosacea symptom severity ( 29771307) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		3 interacting genes: HRAS HSPB1 ZNF512B	17 interacting genes: ESR1 EWSR1 FUS GATA1 HIC1 ITCH KLF1 MLLT1 NCOA1 NEDD4 PGR RARA RARB RARG SMARCA4 TAF15 TP53
Entrez ID		8872	8289
HPRD ID		12586	04319
Ensembl ID		ENSG00000151465	ENSG00000117713
Uniprot IDs		O75794	O14497
PDB IDs			1RYU 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?