CCKBR and CCKAR

Data Source:
HPRD (in vitro)

		CCKBR	CCKAR
Description		cholecystokinin B receptor	cholecystokinin A receptor
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Cholecystokinin Receptor Activity Protein Binding Gastrin Receptor Activity Peptide Hormone Binding Type B Gastrin/cholecystokinin Receptor Binding 1-phosphatidylinositol-3-kinase Regulator Activity	G Protein-coupled Receptor Activity Cholecystokinin Receptor Activity Peptide Hormone Binding
	Biological Process	Gastric Acid Secretion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Population Proliferation Cholecystokinin Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase Activity PH Reduction Digestive Tract Development Gland Development	Neuron Migration G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Forebrain Development Cholecystokinin Signaling Pathway Regulation Of Hormone Secretion
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Peptide ligand-binding receptors G alpha (q) signalling events
Drugs		Pentagastrin Cholecystokinin	Ceruletide Dexloxiglumide Lintitript Cholecystokinin
Diseases
GWAS		Diastolic blood pressure ( 30224653) Early spontaneous preterm birth ( 31194736) Gastroesophageal reflux disease ( 31527586) Malaria ( 31844061)
Interacting Genes		10 interacting genes: ADRB2 ATP13A2 CCK CCKAR CCR4 DRD2 NTM PPP1R9B PTPN11 SLCO1B3	3 interacting genes: CCK CCKBR PPP1R9B
Entrez ID		887	886
HPRD ID		00323	00322
Ensembl ID		ENSG00000110148	ENSG00000163394
Uniprot IDs		E9PIC8 P32239	P32238
PDB IDs		1L4T	1D6G 1HZN 1PB2
Enriched GO Terms of Interacting Partners?
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