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CCN4 and BGN
Data Source:
HPRD
(in vitro)
CCN4
BGN
Description
cellular communication network factor 4
biglycan
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytosol
Extracellular Matrix
Extracellular Region
Extracellular Space
Golgi Lumen
Cell Surface
Transport Vesicle
Extracellular Matrix
Sarcolemma
Lysosomal Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Integrin Binding
Protein Binding
Insulin-like Growth Factor Binding
Heparin Binding
Extracellular Matrix Structural Constituent
Protein Binding
Glycosaminoglycan Binding
Extracellular Matrix Structural Constituent Conferring Compression Resistance
Extracellular Matrix Binding
Biological Process
Osteoblast Differentiation
Regulation Of Cytokine Production
Cell Adhesion
Signal Transduction
Cell-cell Signaling
Positive Regulation Of Smooth Muscle Cell Migration
Wnt Signaling Pathway
Positive Regulation Of Wnt Signaling Pathway
Osteoclast Differentiation
Negative Regulation Of Chondrocyte Differentiation
Glucose Homeostasis
Negative Regulation Of Fat Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Inflammatory Response
Bone Development
Negative Regulation Of Cell Death
Positive Regulation Of Wound Healing
Blood Vessel Remodeling
Biological_process
Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan
Extracellular Matrix Organization
Chondroitin Sulfate Biosynthetic Process
Chondroitin Sulfate Catabolic Process
Dermatan Sulfate Biosynthetic Process
Bone Development
Articular Cartilage Development
Pathways
A tetrasaccharide linker sequence is required for GAG synthesis
Chondroitin sulfate biosynthesis
Dermatan sulfate biosynthesis
CS/DS degradation
ECM proteoglycans
ECM proteoglycans
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Defective CHST14 causes EDS, musculocontractural type
Defective CHSY1 causes TPBS
Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs
Diseases
GWAS
Interacting Genes
4 interacting genes:
BGN
DCN
HOXA1
OTX1
17 interacting genes:
-
APOB
APP
BMP4
CCN4
COL1A1
COL1A2
COL2A1
COL4A2
DAG1
ELN
HSPB2
JPH3
MFAP2
PLA2G1B
TGFB1
TNF
Entrez ID
8840
633
HPRD ID
16019
02359
Ensembl ID
ENSG00000104415
ENSG00000182492
Uniprot IDs
O95388
B4DNL4
P21810
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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