KYAT1 and TRIP13

Data Source:
BioGRID (two hybrid)

		KYAT1	TRIP13
Description		kynurenine aminotransferase 1	thyroid hormone receptor interactor 13
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Protein Binding Transaminase Activity Kynurenine-oxoglutarate Transaminase Activity Pyridoxal Phosphate Binding Protein Homodimerization Activity Glutamine-phenylpyruvate Transaminase Activity Cysteine-S-conjugate Beta-lyase Activity	Transcription Coregulator Activity Protein Binding ATP Binding ATPase Activity Identical Protein Binding
	Biological Process	L-phenylalanine Catabolic Process Tryptophan Catabolic Process Cellular Modified Amino Acid Metabolic Process Cellular Amino Acid Biosynthetic Process Kynurenine Metabolic Process L-kynurenine Catabolic Process	Oocyte Maturation Double-strand Break Repair Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint
Pathways		Tryptophan catabolism Phenylalanine metabolism Glutamate and glutamine metabolism
Drugs		Pyridoxal phosphate Pyridoxamine-5'-Phosphate D-Phenylalanine N(6)-(pyridoxal phosphate)-L-lysine Indoleacetic acid
Diseases
GWAS			Pancreatic cancer ( 25086665)
Interacting Genes		5 interacting genes: APP TRIM55 TRIM63 TRIP13 VAC14	112 interacting genes: ADAM15 AMDHD2 ANKRD10 ARL11 ARSA ASB13 BUB1B C11orf54 C19orf54 C4orf33 CARD14 CD99 CDC20 CDIN1 CEP170B CFP CLIP4 COMT CRMP1 CRYBA2 CYB5R2 DCTN3 DDAH2 DIP2A DPYSL4 DTX2 EEF2KMT FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 IGFN1 IL2RB INCA1 INTS11 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP6-1 KRTAP6-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MBLAC1 MEAK7 METTL15 MGAT5B MORN3 MPPED2 MVP MYEOV NIF3L1 NME4 NTAQ1 PARP11 PAX9 PBLD PCMTD2 PCSK5 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 POLR2L PPP2CA PRKAA2 PRKN PRR13 PSMB8 QARS1 RBPMS RHOXF2 RNF4 SCP2 SDCBP SEC24A SELENBP1 SEMA3B SEMA4G SHARPIN SIGLEC5 SMUG1 SPRYD7 SSC4D STAMBP STAMBPL1 SUMO2 TENT5B TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR VENTX ZMYM5 ZNF34 ZNF655
Entrez ID		883	9319
HPRD ID		02769	05145
Ensembl ID		ENSG00000171097	ENSG00000071539
Uniprot IDs		A8K563 B7Z4W5 Q16773	Q15645
PDB IDs		1W7L 1W7M 1W7N 3FVS 3FVU 3FVX 4WLH 4WLJ 4WP0	5VQ9 5VQA 5WC2 6F0X 6LK0
Enriched GO Terms of Interacting Partners?
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