HESX1 and CATIP

Data Source:
BioGRID (two hybrid)

		HESX1	CATIP
Description		HESX homeobox 1	ciliogenesis associated TTC17 interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Plasma Membrane Actin Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Protein C-terminus Binding Protein N-terminus Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Brain Development Gonad Development Gene Expression Pituitary Gland Development Thyroid Gland Development Otic Vesicle Formation Multicellular Organism Growth Camera-type Eye Development Nose Development Regulation Of Embryonic Development Forebrain Morphogenesis Leukemia Inhibitory Factor Signaling Pathway Stem Cell Differentiation Canonical Wnt Signaling Pathway ERK1 And ERK2 Cascade	Actin Filament Polymerization Cilium Organization
Pathways
Drugs
Diseases		Septo-optic dysplasia Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256)
Interacting Genes		12 interacting genes: C1orf109 CATIP GUCD1 HOXC8 KDM1A NCOR1 NPAS2 PRMT6 PROP1 STAT3 TLE1 UBL5	15 interacting genes: APP BRD9 CEP72 CTNNBL1 DDIT4L GOLGA6L9 HESX1 KRT31 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 MEDAG MTUS2
Entrez ID		8820	375307
HPRD ID		03482	11846
Ensembl ID		ENSG00000163666	ENSG00000158428
Uniprot IDs		A1LQR0 Q9UBX0	Q7Z7H3
PDB IDs		2K40
Enriched GO Terms of Interacting Partners?
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