CREG1 and QSOX1

Data Source:
BioGRID (affinity chromatography technology)

		CREG1	QSOX1
Description		cellular repressor of E1A stimulated genes 1	quiescin sulfhydryl oxidase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Azurophil Granule Lumen Extracellular Exosome	Golgi Membrane Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Golgi Membrane Platelet Alpha Granule Lumen Specific Granule Lumen Intracellular Membrane-bounded Organelle Intercellular Bridge Extracellular Exosome Tertiary Granule Lumen
	Molecular Function	Transcription Corepressor Activity	Protein Disulfide Isomerase Activity Flavin-linked Sulfhydryl Oxidase Activity FAD Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Regulation Of Growth Neutrophil Degranulation Negative Regulation Of Transcription, DNA-templated	Platelet Degranulation Protein Folding Negative Regulation Of Macroautophagy Protein Phosphopantetheinylation Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process Extracellular Matrix Assembly
Pathways		Neutrophil degranulation	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Asthma ( 31959851) Blood protein levels ( 30072576 29875488)	Anorexia nervosa ( 23568457) Blood protein levels ( 29875488) Pulse pressure ( 30224653 30578418)
Interacting Genes		6 interacting genes: CAPN1 IGF2R RB1 RBL1 RBL2 TBP	6 interacting genes: BEGAIN CCR1 CCR6 CHRM4 UBE2D2 UBQLN4
Entrez ID		8804	5768
HPRD ID		09897	06785
Ensembl ID		ENSG00000143162	ENSG00000116260
Uniprot IDs		O75629	A0A140VKE5 O00391 Q13876
PDB IDs		1XHN	3LLI 3LLK 3Q6O 4IJ3
Enriched GO Terms of Interacting Partners?
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