TNFRSF10C and PDZK1IP1

Data Source:
BioGRID (two hybrid)

		TNFRSF10C	PDZK1IP1
Description		TNF receptor superfamily member 10c	PDZK1 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Anchored Component Of Membrane	Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding TRAIL Binding	Protein Binding
	Biological Process	TRAIL-activated Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands
Drugs
Diseases
GWAS		Basophil count ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte count ( 27863252) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Sum basophil neutrophil counts ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252) White blood cell count (basophil) ( 27863252)	Clozapine-induced agranulocytosis ( 25187353)
Interacting Genes		34 interacting genes: APOA1 AQP6 ARL13B ASZ1 CD79A COQ9 CREB3L1 CXCL14 CYB5R3 DNAJC1 ERGIC3 FAM209A GPR152 GPR37L1 KCNJ6 KCNK5 LMNA LRSAM1 MGST1 MRPS18B PDZK1IP1 RAP1A RFLNB SGTA SLC27A6 SLC30A4 SRPK1 SRPK2 STOM SYAP1 TMEM45B TMEM80 TNFSF10 ZHX1	77 interacting genes: AGR3 AIG1 APOA2 APOD AQP2 AQP6 ARL13B ASGR1 C14orf180 C2CD2L CD81 CES1 CLDN19 COPS6 CYB5B CYBC1 EMC6 ERG28 FAM3C FCER1G GALNT15 GAST GIMAP5 GRM2 GYPA HMOX1 ICMT IGFBP5 JAGN1 LEPROTL1 LHFPL5 MIP MYADM MYADML2 NSG1 NUMB PDZK1 PEX16 PGAP2 PLP2 PLPP4 PLPP6 PMP22 RPRM RTP2 SDCBP SFTPC SFXN2 SLC22A1 SLC22A2 SLC35B1 SLC35B4 STRIT1 STX12 THBD TMEM101 TMEM107 TMEM109 TMEM11 TMEM140 TMEM14A TMEM14B TMEM14C TMEM203 TMEM39B TMEM65 TMEM86A TMEM97 TNFRSF10C TRARG1 TRIM54 TSPO2 UPK1B UTP14A VAMP3 YIPF6 ZDHHC17
Entrez ID		8794	10158
HPRD ID		04681	06211
Ensembl ID		ENSG00000173535	ENSG00000162366
Uniprot IDs		O14798	Q13113
PDB IDs
Enriched GO Terms of Interacting Partners?
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