ADAM9 and ADAM32

Data Source:
BioGRID (proximity labelling technology)

		ADAM9	ADAM32
Description		ADAM metallopeptidase domain 9	ADAM metallopeptidase domain 32
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Focal Adhesion Cell Surface Integral Component Of Membrane Intrinsic Component Of External Side Of Plasma Membrane Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Kinase C Binding Integrin Binding Protein Binding Collagen Binding Metallopeptidase Activity SH3 Domain Binding Laminin Binding Metal Ion Binding	Metalloendopeptidase Activity Protein Binding
	Biological Process	Activation Of MAPKK Activity Membrane Protein Ectodomain Proteolysis Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Response To Manganese Ion Cell Migration Keratinocyte Differentiation Positive Regulation Of Cell Migration Membrane Protein Intracellular Domain Proteolysis Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Adhesion Mediated By Integrin Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Macrophage Fusion Response To Tumor Necrosis Factor Monocyte Activation Response To Hydrogen Peroxide Positive Regulation Of Protein Secretion Positive Regulation Of Membrane Protein Ectodomain Proteolysis Response To Glucocorticoid Positive Regulation Of Keratinocyte Migration Response To Calcium Ion Cellular Response To Lipopolysaccharide	Proteolysis Cell Adhesion Binding Of Sperm To Zona Pellucida
Pathways		Collagen degradation
Drugs		INCB7839
Diseases		Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Basophil count ( 32888494)	Herpes simplex virus 2 mgG-1 antibody levels ( 33204752)
Interacting Genes		9 interacting genes: ITGA3 ITGA6 ITGAV MAD2L2 PRKCD SH3D19 SH3GLB1 SNX9 TNF	1 interacting genes: CLDN8
Entrez ID		8754	203102
HPRD ID		04091	16475
Ensembl ID		ENSG00000168615	ENSG00000197140
Uniprot IDs		Q13443	A0A140VJD9 B4DTC2 Q8TC27
PDB IDs		1M1V
Enriched GO Terms of Interacting Partners?
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