TNFSF9 and TNFRSF9

Data Source:
HPRD (in vivo)

		TNFSF9	TNFRSF9
Description		TNF superfamily member 9	TNF receptor superfamily member 9
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Tumor Necrosis Factor Receptor Superfamily Binding	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Immune Response Cell-cell Signaling Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Activated T Cell Proliferation Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Cytotoxic T Cell Differentiation	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation
Pathways		TNFs bind their physiological receptors	TNFs bind their physiological receptors
Drugs			Urelumab
Diseases
GWAS		Metabolite levels ( 23823483)	Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)
Interacting Genes		3 interacting genes: TNFRSF9 TRAF1 TRAF2	7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3
Entrez ID		8744	3604
HPRD ID		05861	03767
Ensembl ID		ENSG00000125657	ENSG00000049249
Uniprot IDs		A0A0U5J8I0 P41273	Q07011
PDB IDs		2X29 6A3V 6BWV 6CPR 6CU0 6D3N 6FIB 6MGE 6MGP	6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2
Enriched GO Terms of Interacting Partners?
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