TNFSF10 and RBM48

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TNFSF10	RBM48
Description		TNF superfamily member 10	RNA binding motif protein 48
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane Extracellular Exosome	Nucleoplasm
	Molecular Function	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Identical Protein Binding TRAIL Binding	RNA Binding Protein Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Cell-cell Signaling Male Gonad Development Response To Insulin Positive Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Caspase activation via Death Receptors in the presence of ligand Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited Dimerization of procaspase-8 TRAIL signaling
Drugs
Diseases
GWAS		Breast cancer ( 28171663) Breast cancer (estrogen-receptor negative) ( 28171663) Carotid plaque burden ( 28282560) Cocaine dependence ( 31212010) Height ( 28552196) Monocyte percentage of white cells ( 27863252) TRAIL levels ( 27989323) Triglyceride levels ( 32203549) Triglycerides ( 30275531)	Idiopathic dilated cardiomyopathy ( 29495422)
Interacting Genes		9 interacting genes: ACP5 CASP3 RBM48 TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11B ZDHHC17	73 interacting genes: AMOT ANXA7 APLP1 ARMC7 ATPAF2 BID BTBD2 C11orf49 CCDC106 CCDC57 CDK5RAP2 CDKN1A CDKN2C COX17 COX5B EIF1AD ERH FAM118B FAM90A1 FXYD6 GADD45G GLYAT GSE1 GSTO1 GYS1 HSF2BP HSPB1 HSPB3 ID2 JMY KIF9 KPNA2 MAFG MAP7D1 MLH1 MLLT3 MNAT1 MPHOSPH6 NTAQ1 NUDT21 OSGEP PAFAH1B3 PCDHA4 PIBF1 PNP POLR1C PPP1R8 PRG2 PRKAB2 PSMD11 RAB27A RAD51D RFC5 RPA2 S100Z SAT1 SCNM1 SERPINB9 SH3GL3 SMN1 SPRED2 SULT1E1 TAF9 TBC1D22B TEKT4 TK1 TNFSF10 TRDMT1 TRIB3 TSR2 VIM WDR33 ZNF24
Entrez ID		8743	84060
HPRD ID		04670	13173
Ensembl ID		ENSG00000121858	ENSG00000127993
Uniprot IDs		P50591 Q6IBA9	Q5RL73
PDB IDs		1D0G 1D2Q 1D4V 1DG6 1DU3 4N90 5CIR
Enriched GO Terms of Interacting Partners?
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