CBR3 and KCNJ15

		CBR3	KCNJ15
Description		carbonyl reductase 3	potassium inwardly rectifying channel subfamily J member 15
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytosol	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Phase I - Functionalization of compounds	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Lumbar spine bone mineral density ( 22504420)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Height ( 31562340) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933)
Interacting Genes		5 interacting genes: ARIH2 BICD2 RAB35 SDCBP UBC	6 interacting genes: IL16 KCNJ16 KCNJ2 KCNJ5 PATJ SNTA1
Entrez ID		874	3772
HPRD ID		07222	03659
Ensembl ID		ENSG00000159231	ENSG00000157551
Uniprot IDs		O75828 V9HW40	Q99712
PDB IDs		2HRB
Enriched GO Terms of Interacting Partners?
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