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RTCA and MIR222
Data Source:
BioGRID
(unspecified method)
RTCA
MIR222
Description
RNA 3'-terminal phosphate cyclase
microRNA 222
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Extracellular Space
Extracellular Vesicle
Molecular Function
RNA Binding
RNA-3'-phosphate Cyclase Activity
ATP Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
RNA Processing
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Angiogenesis
Negative Regulation Of Interleukin-21 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Apoptotic Process
Negative Regulation By Host Of Viral Genome Replication
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Axon Regeneration
Negative Regulation Of Inflammatory Response
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Cardiac Muscle Cell Proliferation
Negative Regulation Of Cell Adhesion Molecule Production
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Schwann Cell Migration
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration
Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes
48 interacting genes:
MIR1-1
MIR106B
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-2
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR199A1
MIR199A2
MIR19B2
MIR200A
MIR205
MIR20B
MIR21
MIR214
MIR222
MIR25
MIR29B2
MIR29C
MIR31
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-2
MIR92A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
OTX2
75 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
PDCD11
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PURA
QARS1
RBFOX2
RBM14
RBM4
RBMS2
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
8634
407007
HPRD ID
15280
Ensembl ID
ENSG00000137996
ENSG00000207725
Uniprot IDs
O00442
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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