CNTNAP4 and APBA1

Data Source:
HPRD (in vivo, in vitro)

		CNTNAP4	APBA1
Description		contactin associated protein family member 4	amyloid beta precursor protein binding family A member 1
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GO Annotations	Cellular Component	Integral Component Of Membrane Presynaptic Membrane Cell Projection	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Dendritic Spine Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function		Amyloid-beta Binding Protein Binding
	Biological Process	Cell Adhesion Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, GABAergic Regulation Of Grooming Behavior	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Neurotransmitter Secretion Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Exocytosis
Pathways			Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Cerebrospinal T-tau levels ( 28247064) Immune response to measles-mumps-rubella vaccine ( 24811271) Response to amphetamines ( 22952603) Response to haloperidol in schizophrenia ( 29503163) Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225) Smoking status (ever vs never smokers) ( 30643258) Sphingolipid levels ( 22359512)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: APBA1 CASK FBXO21 MACF1 MAST3 RANBP10	17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1
Entrez ID		85445	320
HPRD ID		13079	03879
Ensembl ID		ENSG00000152910	ENSG00000107282
Uniprot IDs		A0A087WTA1 Q86YZ8 Q9C0A0	Q02410
PDB IDs		4NXQ	1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?
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