RGS8 and UHMK1

Data Source:
BioGRID (two hybrid)

		RGS8	UHMK1
Description		regulator of G protein signaling 8	U2AF homology motif kinase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Neuronal Cell Body Membrane Perikaryon Synapse	Nucleus Nucleoplasm Golgi Apparatus Axon Midbody Dendrite Cytoplasm Neuronal Ribonucleoprotein Granule
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	RNA Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transferase Activity Ribonucleoprotein Complex Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Dopamine Receptor Signaling Pathway	Cell Cycle Arrest Peptidyl-serine Phosphorylation Neuron Projection Development Positive Regulation Of Translational Initiation Protein Autophosphorylation Regulation Of Protein Export From Nucleus
Pathways		G alpha (i) signalling events G alpha (i) signalling events	Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Drugs
Diseases
GWAS		Morning person ( 30696823)	Bone mineral density (femoral neck) ( 27424934) Bone mineral density (total hip) ( 27424934) Discordance in emotional problems in monozygotic twins ( 27043157) Takayasu arteritis ( 25604533)
Interacting Genes		7 interacting genes: ADRB2 CCDC85B GOLGA2 HOOK2 KRT40 PLEKHF2 UHMK1	9 interacting genes: C1orf109 DEPDC1B LMO1 NDUFAF3 PAM RGS8 STMN1 TMSB4X TSGA10IP
Entrez ID		85397	127933
HPRD ID		06221	12318
Ensembl ID		ENSG00000135824	ENSG00000152332
Uniprot IDs		P57771	Q8TAS1
PDB IDs		2IHD 2ODE 5DO9
Enriched GO Terms of Interacting Partners?
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