DGCR6L and PAK4

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		DGCR6L	PAK4
Description		DiGeorge syndrome critical region gene 6 like	p21 (RAC1) activated kinase 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Golgi Apparatus Adherens Junction Focal Adhesion
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Involved In Cell-cell Adhesion Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process		Regulation Of Cell Growth Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Cell Cycle Signal Transduction Cell Migration Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Angiogenesis Dendritic Spine Development Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways			Activation of RAC1
Drugs			Fostamatinib
Diseases
GWAS
Interacting Genes		28 interacting genes: ADAMTSL4 ATN1 AVPI1 CMTM4 DEUP1 DTNBP1 GATA1 GGA1 HMG20A INIP KCNRG KRT15 KRT19 KRT31 LDB2 LRCH3 LZTS2 MBIP MID2 NAB2 NECAB2 PAK4 POU2AF1 PPP1R13B RIMBP3 SPTA1 ZNF446 ZNF620	25 interacting genes: APP CDC42 DGCR6L DLST FBXO25 FGFR2 G6PD GATAD2A GRB2 H1-1 INKA1 ITGAV ITGB5 LIMK1 POT1 PPARG RAN RHOU SH3RF2 SRPK1 SRPK2 TERF1 YWHAG YWHAQ YWHAZ
Entrez ID		85359	10298
HPRD ID		16800	05675
Ensembl ID		ENSG00000128185	ENSG00000130669
Uniprot IDs		Q9BY27	A0A024R0J1 A0A024R0L8 O96013
PDB IDs			2BVA 2CDZ 2J0I 2OV2 2Q0N 2X4Z 4APP 4FIE 4FIF 4FIG 4FIH 4FII 4FIJ 4JDH 4JDI 4JDJ 4JDK 4L67 4NJD 4O0V 4O0X 4O0Y 4XBR 4XBU 5BMS 5I0B 5UPK 5UPL 5VED 5VEE 5VEF 5XVA 5XVF 5XVG 5ZJW 6WLX 6WLY
Enriched GO Terms of Interacting Partners?
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