COPS3 and KRT80

Data Source:
BioGRID (two hybrid)

		COPS3	KRT80
Description		COP9 signalosome subunit 3	keratin 80
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome	Cytosol Keratin Filament Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification	Keratinization Cornification
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Reticulocyte count ( 32888494)	Diisocyanate-induced asthma ( 25918132) Telomere length ( 24465473)
Interacting Genes		32 interacting genes: ARAF ARF4 C17orf75 CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS7B COPS8 COPS9 CSNK2A1 CSNK2B CUL5 FLAD1 FRS3 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 KRT80 LRP2BP MCPH1 MLF1 NABP1 PRXL2B RAF1 SOS1 TP53	21 interacting genes: C1orf109 COPS3 GINS3 KRT14 KRT15 KRT16 KRT19 KRT20 KRT24 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT38 LCA5L LMO2 MEOX2 UCHL5
Entrez ID		8533	144501
HPRD ID		07262	14068
Ensembl ID		ENSG00000141030	ENSG00000167767
Uniprot IDs		B4DN01 Q9UNS2	Q6KB66
PDB IDs		4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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