KCNAB2 and TNFRSF18

Data Source:
BioGRID (affinity chromatography technology)

		KCNAB2	TNFRSF18
Description		potassium voltage-gated channel subfamily A regulatory beta subunit 2	TNF receptor superfamily member 18
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Specific Granule Membrane Juxtaparanode Region Of Axon Synapse Tertiary Granule Membrane Pinceau Fiber	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding	Tumor Necrosis Factor-activated Receptor Activity Protein Binding
	Biological Process	Neutrophil Degranulation NADPH Oxidation Potassium Ion Transmembrane Transport Regulation Of Action Potential Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface	Positive Regulation Of Leukocyte Migration Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Apoptotic Process Regulation Of Regulatory T Cell Differentiation Positive Regulation Of Cell Adhesion
Pathways		Voltage gated Potassium channels Neutrophil degranulation	TNFs bind their physiological receptors RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)
Drugs		Enflurane Promethazine Miconazole
Diseases
GWAS		Metabolite levels ( 23823483)	Inflammatory bowel disease ( 23128233)
Interacting Genes		8 interacting genes: ATXN1 CD4 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1	6 interacting genes: LNX1 TNFSF18 TRAF1 TRAF2 TRAF3 UBQLN2
Entrez ID		8514	8784
HPRD ID		03090	04879
Ensembl ID		ENSG00000069424	ENSG00000186891
Uniprot IDs		A1PR14 B2R776 Q13303	A0A0R7FDM1 Q9Y5U5
PDB IDs		1ZSX
Enriched GO Terms of Interacting Partners?
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